PRX DERM PERFEXION

ICON Dermatology is excited to offer PRX Perfexion to our patients!  PRX is not a chemical peel. It is in a class by itself and is considered a biostimulator of collagen. This treatment combines TCA, hydrogen peroxide, and kojic acid to build collagen, reduce the appearance of acne scars, tighten the skin, and brighten the complexion. It delivers radiant, youthful skin without the peeling, downtime, or discomfort associated with high-percentage TCA chemical peels.

PRX Perfexion is designed to treat a variety of skin conditions, including:

  • Fine lines and wrinkles

  • Uneven skin texture

  • Hyperpigmentation and age spots

  • Sun damage

  • Acne scars

  • Stretch marks

  • Overall skin laxity

  • Dull complexion


Whether you want to tighten loose skin, reduce unwanted pigmentation, or minimize acne scars, PRX is a safe and effective option for all skin types and skin tones. For full results, we recommend 1 session weekly for 4 weeks. Subsequent maintenance sessions are recommended every few months.

This innovative solution offers a way to rejuvenate your skin while addressing a wide variety of cosmetic and skin health concerns, making it a versatile and effective option for many of our patients.

What is PRX Derm Perfexion?

PRX Derm Perfexion, also known as PRX-T33® or CALM Glow, is not a typical chemical peel. It’s a unique treatment that bypasses the outer epidermis, penetrating the deeper layers of the skin to stimulate collagen production, cell renewal, and overall rejuvenation. Unlike traditional peels, PRX Derm Perfexion doesn’t cause peeling, redness, or extensive downtime, making it an excellent option for those seeking transformative results without disrupting their daily routine.

Originally developed to treat scars in children, PRX Derm Perfexion is gentle enough for sensitive areas like the eyes and effective for improving the skin on the face, neck, décolletage, abdomen, and more.

How PRX Derm Perfexion Works

This revolutionary treatment combines a proprietary blend of trichloroacetic acid (TCA), kojic acid, and hydrogen peroxide, each contributing to the treatment’s powerful yet gentle effects:

  • TCA (33%) stimulates fibroblasts (connective tissue cells) to boost collagen production, exfoliate, and reduce inflammation.

  • Kojic Acid brightens the skin, suppressing melanin production to improve uneven tone and pigmentation.

  • Hydrogen Peroxide cleanses the skin while enhancing the effectiveness of the active ingredients by sensitizing skin cells.

Benefits of PRX Derm Perfexion

PRX Derm Perfexion offers numerous benefits, making it a favorite among our patients:

  • Smooths fine lines and wrinkles

  • Improves skin tone and texture for a radiant complexion

  • Diminishes acne scars, stretch marks, and hyperpigmentation

  • Safe for all skin types, tones, and sensitive areas

  • Non-invasive with little to no discomfort

  • Requires no downtime, allowing patients to resume daily activities immediately

  • Offers both immediate and long-term results with collagen stimulation

What to Expect During a PRX Derm Perfexion Treatment

PRX Derm Perfexion sessions are quick, comfortable, and effective. Each treatment typically lasts 30–45 minutes and involves the following steps:

  1. Cleansing: Your skin is thoroughly cleaned to prepare for treatment.

  2. Application: The PRX solution is massaged into the skin in layers (usually 2–5 applications, depending on your skin’s needs).

  3. Moisturizing: After the solution is absorbed, your skin is rinsed, and a deep moisturizer is applied to enhance hydration and comfort.

Most patients report minimal tingling or itching during the treatment, with no need for numbing or anesthetic.

What Can PRX Derm Perfexion Treat?

PRX Derm Perfexion is incredibly versatile and effective for addressing a wide range of skin concerns, including:

  • Fine lines and wrinkles: Tighten and smooth aging skin.

  • Hyperpigmentation: Improve uneven tone, melasma, and dark spots.

  • Acne scars: Minimize the appearance of atrophic and indented scars.

  • Stretch marks: Fade red and white marks on various body areas.

  • Photoaging: Reverse the effects of sun damage for a rejuvenated complexion.

  • Dull skin: Restore brightness and vitality to tired, lackluster skin.

Who is a Good Candidate for PRX Derm Perfexion?

PRX Derm Perfexion is safe for men and women of all ages, skin types, and tones. It’s ideal for individuals seeking non-invasive skin rejuvenation without downtime. However, it may not be suitable for those who:

  • Are pregnant or breastfeeding

  • Have active skin infections, wounds, or sores in the treatment area

  • Have a known allergy to any of the active ingredients

  • Have extremely sensitive skin

Our board-certified providers at ICON will evaluate your skin during a consultation to determine if PRX Derm Perfexion is the right treatment for you.

Results and Maintenance

One of the most exciting aspects of PRX Derm Perfexion is its ability to deliver both immediate and long-term results:

  • Short-Term: Skin appears tighter, brighter, and more hydrated after just one session.

  • Long-Term: Collagen production continues to improve skin texture, elasticity, and overall health over time.

For optimal results, we typically recommend:

  • General Skin Rejuvenation: 1 session per week for 4 weeks.

  • Hyperpigmentation or Acne Scars: 1 session per week for 4–6 weeks.

  • Stretch Marks: 1 session per week for 4–10 weeks.

After completing your initial series, maintenance treatments can be scheduled every few months or annually, depending on your needs and goals.

Can PRX Derm Perfexion be Combined with Other Treatments?

Yes! ICON has developed unique protocols using PRX treatments in conjunction with other treatments to maximize your results. Depending on which other treatment you are having, PRX may be performed a week prior to or immediately beforehand. This will be discussed during your consultation.

Why Choose ICON Dermatology for PRX Derm Perfexion?

At ICON Dermatology, we are committed to delivering personalized care and the latest in skin rejuvenation technology. Our experienced, board-certified dermatologists tailor each treatment plan to your unique skin concerns, ensuring optimal results and a comfortable experience.

When you choose ICON Dermatology, you can trust that you’re in expert hands. We prioritize patient safety, education, and satisfaction, guiding you every step of the way on your journey to healthier, more beautiful skin.

Schedule a PRX Derm Perfexion Treatment

Ready to experience the benefits of PRX Derm Perfexion for yourself? Whether you want to address fine lines, acne scars, or dull skin, this innovative treatment can help you achieve the glowing, youthful complexion you deserve. To learn what this treatment might do for you, please schedule an appointment online or call us at 301-810- 3600.